During shuttle missions, Space Shuttle audio is retransmitted on W2FCL/R, 146.61 MHz thanks to the Land Rovers Amateur Radio Club in Randolph, NJ.
The Shuttle Amateur Radio Experiment (SAREX) is a long-running program to use amateur radio equipment on board the Space Shuttle to involve students in exchanging questions and answers with astronauts on orbit. More than 200 schools have participated to date. It is also used to conduct communications experiments with amateur radio operators on the ground. [Excerpt from NASA's SAREX home page.]